Articles
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Trastuzumab Resistance in HER2+ Breast Cancer: When Cancer Rewires the Network
By Prof. Dr. Alexander Kel • September 3, 2026 -

Why Gene Signatures Fail in Another Cohort
By Prof. Dr. Alexander Kel • June 9, 2026 -

From Gene Lists to Biological Causes: Decoding the “Why” Behind Gene Expression Changes
By Prof. Dr. Alexander Kel • March 12, 2026 -

From Regulatory Networks to Longevity: A Genome Enhancer Case Study
By Prof. Dr. Alexander Kel • February 17, 2026 -

Unmasking Huntington’s Disease: From a Single Gene to a Network of Pathological Signals
By Prof. Dr. Alexander Kel • February 10, 2026 -

Can Transcription Factors Turn Back the Clock on Aging?
By Prof. Dr. Alexander Kel • January 22, 2026 -

Molecular Mechanisms of Glioblastoma: Insights from the HumanPSD Database
By Prof. Dr. Alexander Kel • November 25, 2025 -

FOXO3: The Longevity Switch Inside Our Cells — Decoding the Master Regulator of Aging, Stress, and Disease
By Prof. Dr. Alexander Kel • November 17, 2025 -

Glioblastoma’s vicious circle — and how we can break It
By Prof. Dr. Alexander Kel • November 4, 2025 -

FOXP3: Master Regulator of Immune Tolerance and T-Cell Identity
By Prof. Dr. Alexander Kel • October 16, 2025 -

Who came first – Transcription Factors or miRNAs? Exploring their intertwined roles
By Prof. Dr. Alexander Kel • October 7, 2025 -

MEALR: Motif Enrichment Analysis by Logistic Regression (White Paper)
By Philip Stegmaier • September 29, 2025 -

From Data to Discovery: The Story of LCTA – A Novel Class of Anticancer Compounds Targeting Thioredoxin Reductase
By Prof. Dr. Alexander Kel • August 31, 2025 -

Canonical vs. Non-Canonical Signaling: TNF Superfamily Members Activate Non-Canonical NF-κB Signaling
By Prof. Dr. Alexander Kel • August 19, 2025 -

Disease Similarity Maps: A Visual Resource for Researchers
By Prof. Dr. Alexander Kel • July 22, 2025 -

Designing a personalized COPD gene expression panel
By Prof. Dr. Alexander Kel • July 22, 2025 -

Upstream Analysis: Identifying Master Switches in Gene Regulation
By Prof. Dr. Alexander Kel • June 25, 2025 -

Multi-omics integration
By Prof. Dr. Alexander Kel • June 3, 2025 -

What are Transcription factors?
By Prof. Dr. Edgar Wingender • June 1, 2025
