Genome Enhancer is a fully automated pipeline for patient’s multi-omics data analysis. It generates a comprehensive report about the personalized drug targets identified for a certain patient, or a group of patients, and the drugs that may be effective in this case. Proven applications include cancer, neurodegenerative diseases, infectious diseases, diabetes and metabolic diseases, hypertension. Genome Enhancer is using TRANSFAC®, TRANSPATH® and HumanPSD™ databases for the performed analysis. Learn more about Genome Enhancer.
The geneXplain platform is designed to ease the life of the bioinformatics expert who is in charge to evaluate experimental high-throughput data, but also effectively supports the experimental researcher to interpret his/her valuable data with an intuitive user interface. You are cordially invited to learn more about the geneXplain platform.
The gold standard in the field of transcriptional regulation. This database comprises a unique collection of information about transcription factors (TFs), their genomic binding sites and binding site models (positional weight matrices), suitable for search for new TF binding sites. Learn more about the TRANSFAC database.
In addition to the TRANSPATH database (see above), we make available the world’s largest collection of interactions and pathways, the GeneWays database, through our geneXplain platform.
The Human Proteome Survey Database (HumanPSD) is a rich compendium of human, mouse and rat proteins, their disease associations, biomarker properties and drug associations.
The most comprehensive information repository on enzymes and enzyme ligand data. BRENDA is an indispensable resource when working with metabolic networks.
Based on the world’s largest data collections pertaining to the biological activities of chemical compounds and their structures, PASS and PharmaExpert enable users to identify potential lead structures out of millions of chemical substances, thereby efficiently shortening development times for specific drugs or molecular probes for research purposes.
PharmaExpert analyzes the relationships between biological activities, drug-drug interactions and multiple targeting of chemical compounds and selects compounds that have a pre-defined biological activity. It helps answer a question like “How to select the most promising compounds among those known to interact with the selected protein?
Particularly valuable for experts is the program GUSAR, which enables construction of highly specific models based on own data sets.
Find history in our archive.
September 26, 2022
Our new COPreDict project devoted to COPD progression tracking and prospective treatment selection has started. Find all details here >>
September 16, 2022
The new Classroom License is available now staring from 400€ (VAT not included)
September 8, 2022
Check out our series of brief summaries on transcription factors, the role of which in cancer has been shown in recent publications.
August 01, 2022
The 2022.2 release of BRENDA is available! Check out this important resource.
July 12, 2022
Join us on July 12th at 6:30 PM CEST for a free webseminar “Young cerebrospinal fluid restores oligodendrogenesis and memory in aged mice via Fgf17” based on the widely shared eponymous Nature paper. Find details and registration link here.