geneXplain

Discover with precision

Apply high-quality knowledge of diseases, drugs, pathways, and gene regulation.

Get two real ovarian cancer reports linking multi-omics data to mechanisms, drug targets and therapies.

Start with what you want to do

Pick your goal — we’ll point you to the right way in.

TRANSFAC Workspace
Analyze your data yourself

TRANSFAC Workspace

Run your own analyses in one integrated workspace — from transcription factor binding sites and signaling networks to disease mechanisms, biomarkers and drug targets. No coding required.

TRANSFAC Expert
Discover mechanisms with us

TRANSFAC Expert

Work with a geneXplain scientist to turn your data into mechanistic insight, prioritized candidates, and testable hypotheses.

TRANSFAC Knowledge Graph
Build AI on our data

TRANSFAC Knowledge Graph

License 38+ years of curated biology as data — grounded, literature-traceable knowledge to train and validate your own AI models.


Specialist databases

Purpose-built resources for chemistry and enzymes.

Chemo-Informatics (PASS, PHARMAEXPERT)
Predict compound activity

Chemo-Informatics (PASS, PHARMAEXPERT)

Predict the biological activity of chemical compounds with the structure–activity relationship (SAR) approach, then analyze activity networks and drug interactions.

BRENDA
Explore enzymes & metabolites

BRENDA

The most comprehensive enzyme database, powered by an industry-standard systems-biology platform — master the enzymes and metabolites.

Our partners

Karolinska Institutet
Hannover Medical School (MHH)
VIB
Luxembourg Institute of Health
Royal College of Surgeons in Ireland
INSERM

Additional project partners

Partner names are presented at organization level and reflect the information available on the cited pages at the time of review.

Testimonials

“GeneXplain’s databases and software tools are very helpful for our research. The training program is absolutely amazing. It clearly shows to my students how to maximize results of analysis of our omics data! They can learn all the steps of the analysis — from raw data preprocessing to unraveling the hidden molecular mechanisms behind the pathology we’re studying.”

Dr. Sudipto Das, portrait

Dr. Sudipto Das

Lecturer, Pharmacy and Biomolecular Sciences · Royal College of Surgeons in Ireland (RCSI)

“I used geneXplain software and databases in several projects to map our genomics, transcriptomics, and proteomics data onto affected pathways and master regulators. It was very helpful for interpretation of our results. GeneXplain team was always very responsive to our requests to customize workflows!”

VP

Victor P. Andreev, PhD, DSc

Senior Research Scientist, Arbor Research Collaborative for Health · Ann Arbor, Michigan, USA

“The geneXplain “Click and Run” bioinformatics approach is absolutely perfect for my needs! I’ve discovered how to uncover the biological significance hidden within my data.”

Maria Smetanina, portrait

Maria Smetanina

Baylor College of Medicine · Houston, Texas, USA