Genome Enhancer is a fully automated pipeline for patient’s multi-omics data analysis. It generates a comprehensive report about the personalized drug targets identified for a certain patient, or a group of patients, and the drugs that may be effective in this case. Proven applications include cancer, neurodegenerative diseases, infectious diseases, diabetes and metabolic diseases. Genome Enhancer is using TRANSFAC®, TRANSPATH® and HumanPSD™ databases for the performed analysis. Learn more about Genome Enhancer.
The geneXplain platform is designed to ease the life of the bioinformatics expert who is in charge to evaluate experimental high-throughput data, but also effectively supports the experimental researcher to interpret his/her valuable data with an intuitive user interface. You are cordially invited to learn more about the geneXplain platform.
The gold standard in the field of transcriptional regulation. This database comprises a unique collection of information about transcription factors (TFs), their genomic binding sites and binding site models (positional weight matrices), suitable for search for new TF binding sites. Learn more about the TRANSFAC database.
In addition to the TRANSPATH database (see above), we make available the world’s largest collection of interactions and pathways, the GeneWays database, through our geneXplain platform.
The Human Proteome Survey Database (HumanPSD) is a rich compendium of human, mouse and rat proteins, their disease associations, biomarker properties and drug associations.
The most comprehensive information repository on enzymes and enzyme ligand data. BRENDA is an indispensable resource when working with metabolic networks.
Based on the world’s largest data collections pertaining to the biological activities of chemical compounds and their structures, PASS and PharmaExpert enable users to identify potential lead structures out of millions of chemical substances, thereby efficiently shortening development times for specific drugs or molecular probes for research purposes.
PharmaExpert analyzes the relationships between biological activities, drug-drug interactions and multiple targeting of chemical compounds and selects compounds that have a pre-defined biological activity. It helps answer a question like “How to select the most promising compounds among those known to interact with the selected protein?
Particularly valuable for experts is the program GUSAR, which enables construction of highly specific models based on own data sets.
Find history in our archive.
September 23, 2021
Join us for geneXplain’s open day devoted to the World Cancer Research Day on September 23rd at 3 PM CEST. Check the event page for further info and registration details.
September 10, 2021
Don’t miss the chance to attend geneXplain’s contribution to the BioNetVisA workshop at the [BC]2 conference on Monday September 13, 2021.
In his online-talk entitled “Personalized anti-cancer drug treatment choice using RNA-seq and network analysis” Dr. Alexander Kel will present the application of Genome Enhancer to cancer patient data.
September 9, 2021
TRANSFAC® 2.0 is now out! Check out this great resource for gene regulation studies.