Use cases

In a recently published study, geneXplain’s approach to a causative upstream analysis was applied to toxicological datasets, revealing master regulators of the toxic effect of naphthalene onto liver and lung tissue. These regulators were clearly associated with both tumorigenic and apoptotic processes.

Promoter analysis for matches with a model comprising a set of transcription factor binding sites (TFBSs). (Click image for an enlarged view.)