HumanPSD™ release 2020.3
The Human Proteome Survey Database (HumanPSDTM) with focus on human proteins as disease biomarkers and drug targets contains these new features:
- Quick access box on start page
Browse all human gene, disease, and drug entries in HumanPSD and access the detailed reports directly.
UniProtKB accessions, EntrezGene IDs, and BKL primary and secondary accessions can now be used as input in a keyword search.
- Disease entry for COVID-19
A dedicated entry for COVID-19 based on data from the MeSH 2021 preview release was included. It contains more than 1,900 clinical trials related to the disease provided by the AACT database and clinicaltrials.gov.
- More Clinical Trial and Biomarker data
New data from clinicaltrials.gov and manual disease biomarker curation by experts have increased the number of CT-Disease-Drug assignments to 695,136 and the number of disease annotations to 344,832.
Improved processing of clinical trials data using the AACT database has contributed to these elevated numbers.
Thank you very much for your interest in our programs!
Please contact us and you will be provided with your free trial version.
The basic information unit is a “locus report”, which summarizes the existing knowledge about the product(s) of a gene. It is part of a hierarchy, with individual proteins (isoforms such as splice variants) encoded by a gene at a level under the locus report, and summarizing features of the orthologs of human, mouse and rat origin at a higher level.
HumanPSDTM Statistics (download)
HumanPSDTM Features (download)
HumanPSD FlyerTM (download)
Stegmaier, P., Krull, M., Voss, N., Kel, A.E., Wingender, E. (2010) Molecular mechanistic associations of human diseases. BMC Syst Biol. 4, 124. doi: 10.1186/1752-0509-4-124. PubMed.
Michael, H., Hogan, J., Kel, A., Kel-Margoulis, O., Schacherer, F., Voss, N., Wingender, E. (2008) Building a knowledge base for systems pathology. Brief. Bioinform. 9, 518-531. doi: 10.1093/bib/bbn038. PubMed.
Wingender, E., Crass, T., Hogan, J.D., Kel, A.E., Kel-Margoulis, O.V., Potapov, A.P. (2007) Integrative content-driven concepts for bioinformatics “beyond the cell”. J Biosci. 32, 169-180. PubMed.
Hodges PE, Carrico, P.M., Hogan, J.D., O’Neill, K.E., Owen, J.J., Mangan, M., Davis, B.P., Brooks, J.E., Garrels, J.I. (2002) Annotating the human proteome: the Human Proteome Survey Database (HumanPSD) and an in-depth target database for G protein-coupled receptors (GPCR-PD) from Incyte Genomics. Nucleic Acids Res. 30:137-141. PubMed.
HumanPSD is a trademark of QIAGEN GmbH.