Database content

The core of TRANSFAC® comprises contents of two domains: One documents transcription factor-binding sites (TFBSs, SITES), usually in promoters or enhancers, and the derived DNA binding motifs in form of positional weight matrices (PWMs, MATRICES). The other describes the transcription factors (TFs, FACTORS) subsumed to classes, based on the general properties of their DNA-binding domains, which has been expanded to a comprehensive classification (TF CLASSIFICATION), the latest version of which can be found here.

TRANSFAC search interface

The TRANSFAC® database search interface is provided in the web browser online. 

Here we show how to operate in the basic interface and perform searches in the TRANSFAC® database.