Reaction network:

TRANSPATH® database is one of the most comprehensive repositories of signal transduction reactions in mammalian cells. It collects over 1,200,000 experimentally proven reactions of phosphorylation, acetylation, ubiquitination, translocation and other types of reactions involved in signal transduction. These reactions build a highly connected regulatory reference network which is used for analysis and reconstruction of molecular mechanisms of diseases, identification of master-regulators and drug targets.

TRANSPATH® reaction reference network (a fragment)

A fragment of TRANSPATH(R) reaction reference network. Pink nodes correspond to the “master-regulators”, and blue nodes correspod to “effectors”.

View reaction report