TRANSFAC 2.0 — The Most Comprehensive Transcription Factor Resource

Explore TRANSFAC packages

Transfac Basic

Discover TF binding sites in promoters and enhancers of your genes

Request price

About TRANSFAC BASIC

What is included:

Database Features

  • PWMs over 10,000 for animals, plants, and fungi
  • TF Sites experimentally proven and ChIP-seq
  • Promoters, Enhancers tissue and cell type-specific ( Hi-C, CAGE, single cell)

Tool Features

  • Site search and enrichment automatic cut-off optimisation (Match, FMatch, CMsearch)
  • Tissue specific TF binding sites in promoters and enhancers 
    (MATCH Suite)
  • AI and ML reveal site combinatorics
  • Omics analysis RNA-seq, ChIP-seq, ATAC-seq, CUT&RUN, WGS, WES, single cell
  • Easy GUI for no-coding bioinformatics
  • Over 200 tools and pipelines Analyze genes, FASTA, FASTQ, VCF, BED.
  • Cloud Storage 100GB
  • API run our tools from your local Python and R

Statistics

Transfac Pathways

Reconstruct signal transduction network controlling your genes

Request price

About TRANSFAC PATHWAYS

What is included:

Database Features

  • All TRANSFAC Basic database features
  • Pathways signaling and metabolic
  • Reaction network over 1,200,000  experimentally proven reactions
  • Upstream of TFs – links between transcription factors and signaling cascades

Tool Features

  • All TRANSFAC Basic capabilities
  • Master regulators — search upstream of TFs using modern graph algorithm
  • Upstream analysis — promoter + network analysis
  • SBGN viewer — web‑based pathway/network editable diagrams
  • ODE modeling — the fastest and most robust simulation engine
  • End‑to‑end multi‑omics workflow – (upload, integrate, and analyse genomics, transcriptomics, epigenomics, proteomics and metabolomics)

Statistics

Transfac Diseases

Identify drug targets and disease biomarkers

Request price

About TRANSFAC DISEASES

What is included:

Database Features

  • All TRANSFAC Pathways database features
  • Disease mechanism discovery with AI and upstream analysis for over 3,900 human diseases
  • Biomarkers over 140,000 (causal, correlative, MOA) and over 2,000,000 annotations
  • Drugs and targets over 10,000 drugs and over 55,000 targets
  • Clinical trials over 1,100,000 trial-disease pairs

Tool Features

  • All TRANSFAC Pathways capabilities
  • Multi-omics integration “All Five”: transcriptomics, genomics, epigenomics, proteomics, metabolomics
  • Drug repurposing using networks and chemoinformatics
  • Fully automatic one-click solution
  • Detailed report with everything needed for your paper

Statistics

TRANSFAC is the gold-standard database of eukaryotic transcription factors (TFs), their binding sites, and DNA binding models — manually curated, experimentally validated, and integrated with powerful analysis tools.

Whether you’re exploring gene regulation, reconstructing signaling networks, or hunting disease biomarkers, the TRANSFAC suite gives you the knowledge base and analysis tools you need.

TRANSFAC versus JASPAR