Systems Biology

Multi-Omics Integration for Pathway Discovery: Insights from an Ovarian Cancer Case Study What is Multi-Omics Integration and Why Does It Matter? Multi-omics integration is combining multiple layers of “omics” data (genomics, transcriptomics, epigenomics, proteomics etc) to get a systems-level view of biology. Instead of analyzing one data type in isolation,…

Transcription factors (TFs) are the main regulators of gene activities. They play a central role in nearly every cellular process, thereby controlling practically any physiological phenomenon. Among them are the differentiation of pluripotent stem cells to highly specialized tissue cells, cellular responses to hormones, and sex development, just to name…