TRANSFAC: Your gateway to precision gene regulation
TRANSFAC isn’t just another database—it’s the original, the one everyone else imitates.
When precision, clarity, and actionable insights from genomic data matter, TRANSFAC is your best ally.
Motifs & TF-Binding Sites: Precision Defined
10,000+ Curated PWMs
Access the largest, highest-quality library of eukaryotic transcription factor motifs
Instant Variant Impact
Quickly see how genomic variants impact transcription factor binding, streamlining mutation interpretation
AI-Enhanced Predictions
Accurately predict TF interactions, saving time and increasing confidence in your results
Key outcomes:
Eliminate guesswork in genomic interpretation, dramatically accelerating research timelines
Unique features:
Unlike simplified motif databases, TRANSFAC’s PWMs are extensively validated, offering far superior reliability
Promoters & Enhancers: Explore Deeper, Find More
Experimentally Validated Data
Leverage the largest collection of experimentally proven TF-gene interactions for robust insights
Discover Hidden Regulators
Detect complex regulatory interactions others overlook, including synergistic composite elements
Rapid Target Identification
Effortlessly pinpoint precise targets tailored to specific tissues or conditions
Key outcomes:
Quickly transition from raw data to validated hypotheses, improving research efficiency and accuracy
Unique features:
While others rely on computational predictions alone, TRANSFAC provides unmatched experimental validation
Pathways & Master Regulators: Connect the Biological Dots
Visual Network Clarity
Simplify complex data using over 1.2 million expert-validated molecular interactions
Custom Network Creation
Build personalized pathways effortlessly, tailored specifically to your research questions
Uncover Master Regulators
Identify critical upstream drivers missed by traditional approaches, highlighting impactful therapeutic targets
Key outcomes:
Move beyond surface-level pathway analysis to deeply understand disease mechanisms
Unique features:
TRANSFAC integrates uniquely curated pathway data, far exceeding standard pathway tools
Multi-Omics: Integration Without Complexity
Automated Analysis Pipeline
Easily integrate genomics, transcriptomics, proteomics, epigenomics, and metabolomics data
Advanced Upstream Analysis
Precisely identify master transcriptional regulators from complex multi-omics datasets
Key outcomes:
Streamline multi-omics analyses, drastically reducing time from data to actionable insights
Unique features:
Unlike fragmented analysis tools, TRANSFAC provides comprehensive, fully automated multi-omics integration
Biomarkers & Drug Discovery: Faster Insights, Better Outcomes
Extensive Biomarker Database
Over 140,000 curated gene-disease and drug-target associations
Disease Mechanism Reconstruction
Effortlessly reconstruct molecular drivers behind diseases, enhancing therapeutic strategies
Key outcomes:
Rapidly discover biomarkers and drug targets, greatly improving drug development timelines
Unique features:
TRANSFAC’s biomarker data depth and disease mechanism insights surpass competitors significantly
Precision Medicine: Truly Personalized, Highly Effective
Personalized Therapeutic Insights
Quickly identify patient-specific drug targets from individual multi-omics profiles
Drug Repurposing Excellence
Efficiently explore off-label and novel drug combinations for personalized care
Key outcomes:
Achieve truly personalized treatment strategies, greatly improving patient outcomes
Unique features:
TRANSFAC uniquely integrates omics data to deliver actionable personalized therapeutic insights
Powerful, User-Friendly Workflows
200+ Ready-to-Use Pipelines
Effortlessly execute complex analyses without coding
Visual Pipeline Customization
Intuitively tailor your analyses with visual programming
Flexible APIs & Visualization Tools
Seamlessly manage workflows and visualize results intuitively
Key outcomes:
Remove bioinformatics bottlenecks, empowering biologists to directly drive data analysis
Unique features:
TRANSFAC’s user-friendly workflows eliminate the steep learning curves typical of competitor platforms
Why Choose TRANSFAC? Simply Unmatched.
35 Years of Expertise
Meticulous curation ensures unparalleled accuracy and trustworthiness
Largest Validated Dataset
The gold standard for experimentally proven TF binding sites
Robust AI Integration
Advanced algorithms deliver exceptionally precise regulatory predictions
Comprehensive Systems Biology Approach
Seamlessly integrates transcription factors, pathways, and disease mechanisms
TRANSFAC:
Precision, Power, and Proven Insights for Gene Regulation.