TRANSPATH® release 2021.2
The TRANSPATH® database on mammalian signal transduction and metabolic pathways contains these new data features:
- BIOPLEX 1 and 3 interactome data imported
Integration of BIOPLEX human interaction data from release 1 and 3 resulted in 131,566 new and 60,151 reactions updated with additional experimental evidence.
- Human Reference Protein Interactome (HuRI) integrated
45,468 new reactions were imported from the HuRI mapping project. In addition, 6,371 existing reactions were updated with experimental evidence from HuRI.
- Increase in number of reactions
29,662 new binding reactions between proteins in human have been added, among them e.g. from interactome in mitochondria and the bromodomain protein interactome.
- Update of links to pathway databases
Links from genes/proteins to the pathway databases Reactome (version 77) and Wikipathways (20210610) have been updated.
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