PWMs:

Binding sites referring to the same TF are merged into a positional weight matrix. Such a matrix reflects the frequency with which each nucleotide is found in each position of this TF’s binding sites and, thus, the base preference in each position.

Get free multi-omics reports to your Email

  • Multi-Omics Case Study Report – Ovarian Neoplasm Analysis
  • MATCH Suite Arabidopsis gene set analysis report
Blog post body lead magnet (#93)

Here is an example of PWM for binding sites for E2F-1 transcription factors.

TRANSFAC® includes over 10,000 Positional Weight Matrices (PWMs) that are robust models for predicting TF binding sites in genomes of various animals, plants, and fungi.

Matrix-Report_VCREB_Q4_01Download