PWMs:

Binding sites referring to the same TF are merged into a positional weight matrix. Such a matrix reflects the frequency with which each nucleotide is found in each position of this TF’s binding sites and, thus, the base preference in each position.

Here is an example of PWM for binding sites for E2F-1 transcription factors.

TRANSFAC® includes over 10,000 Positional Weight Matrices (PWMs) that are robust models for predicting TF binding sites in genomes of various animals, plants, and fungi.

Matrix-Report_VCREB_Q4_01Download