PWMs:

Binding sites referring to the same TF are merged into a positional weight matrix. Such a matrix reflects the frequency with which each nucleotide is found in each position of this TF’s binding sites and, thus, the base preference in each position.

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Here is an example of PWM for binding sites for E2F-1 transcription factors.

TRANSFAC® includes over 10,000 Positional Weight Matrices (PWMs) that are robust models for predicting TF binding sites in genomes of various animals, plants, and fungi.

Matrix-Report_VCREB_Q4_01Download