Release 2024.1
Release announcement
The geneXplain team is proud to present the new release of its products: TRANSFAC®, TRANSPATH® and HumanPSD™ databases release 2024.1, geneXplain® platform release 7.4 and Genome Enhancer release 3.4.
TRANSFAC® 2.0 2024.1 comes with the following new features:
New TRANSFAC analysis tool
In its new 3.0 release, the MATCH Suite toolbox of TRANSFAC 2.0 was updated with the functionality of model organisms’ gene regulation analysis. Now, gene sets coming from Human, Mouse, or Rat can be analyzed based on functional categorization. Search can be narrowed down to particular transcription factors of interest. A report example produced as the result of mouse gene set analysis can be viewed here.
For more details please explore the TRANSFAC® 2024.1 new features and database statistics.
TRANSPATH® 2024.1 comes with the following new features:
Reactome integration
1,365 human pathways consisting of 12,786 reactions have been integrated and converted to the TRANSPATH data model. Subsequent reactions can be viewed in dedicated pathway reports and the Pathfinder tool visualizes whole pathways with options for e.g. editing and network expansion.
Increase in number of reactions
6,289 new binding reactions from recent publications have been added.
Update of links to Wikipathways and Reactome
Links from genes/proteins to the pathway database Wikipathways (
For more details please explore the TRANSPATH® 2024.1 new features and database statistics.
HumanPSD™ 2024.1 comes with the following new features:
Biomarker and drug target data update
The number of disease annotations increased to 408,644 and the number of unique gene/biomarker – disease assignments to 135,700.
Newly FDA-approved drugs (Sep 2023 – Mar 2024), their indication, and their protein target information were added.
For more details please explore the HumanPSD™ 2024.1 new features and database statistics.
geneXplain® platform 7.4 release comes with the following new features:
HOMER tool integration
The HOMER tool for motif discovery was integrated into the geneXplain platform. It is represented by two methods located inside the Galaxy section of the platform: the FindMotifs tool for gene list analysis and FindMotifsGenome tool for analysis of BED files.
Databases update
TRANSFAC®, TRANSPATH® and HumanPSD™ databases update to release 2024.1. Please note that with the new release the analysis results might vary from the previous ones.
For more details, explore the full new features list of
Genome Enhancer 3.4 release comes with the following new features:
Databases update
TRANSFAC®, TRANSPATH® and HumanPSD™ databases update to release 2024.1. Please note that with the new release the analysis results might vary from the previous ones.
Demo reports update
The new Genome Enhancer demo reports can be found here.
For more details, explore the full new features list of