Information downloads

×

Independent PASS applications

Most recent independent publications reporting on PASS applications:

da Silva C.H., da Silva V.B., Resende J., Rodrigues P.F., Bononi F.C., Benevenuto C.G., Taft C.A. (2010) Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy. J. Mol. Graph. Model. 28:513-523. PubMed.
(includes experimental verifications of PASS predictions)

Navarrete-Vázquez G., Hidalgo-Figueroa S., Torres-Piedra M., Vergara-Galicia J., Rivera-Leyva J.C., Estrada-Soto S., León-Rivera I., Aguilar-Guardarrama B., Rios-Gómez Y., Villalobos-Molina R., Ibarra-Barajas M. (2010) Synthesis, vasorelaxant activity and antihypertensive effect of benzo[d]imidazole derivatives. Bioorg. Med. Chem. 18:3985-3991. PubMed.
(includes experimental verifications of PASS predictions)

Torres-Piedra M., Ortiz-Andrade R., Villalobos-Molina R., Singh N., Medina-Franco J.L., Webster S.P., Binnie M., Navarrete-Vázquez G., Estrada-Soto S. (2010) A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition. Eur. J. Med. Chem. 45:2606-2612. PubMed.
(includes experimental verifications of PASS predictions)

Mustafayeva K., Di Giorgio C., Elias R., Kerimov Y., Ollivier E., De Méo M. (2010) DNA-damaging, mutagenic, and clastogenic activities of gentiopicroside isolated from Cephalaria kotschyi roots. J. Nat. Prod. 73:99-103. PubMed.
(includes PASS predictions without experimental verifications)

Pospieszny T., Małecka I., Paryzek Z. (2010) A practical synthesis and spectroscopic study of new potentially biologically active S-lithocholic acid substituted derivatives of 2-thiouracil. Tetrahedron Letters. 51:4166-4169.
(synthesis of new compounds and predictions of their biological activities by PASS)