Unlock the Power of Free Gene-regulation.com
Ready to explore the fundamental drivers of gene expression?
In this webinar, we will show you how to launch your research journey at gene-regulation.com using the free access to TRANSFAC®, the renowned database for transcription factors and their binding sites.
Discover how to tap into rich regulatory information and set the foundation for groundbreaking insights in genomics, transcriptomics, and systems biology.
Start Your Gene Regulation Journey
What You Will Learn
Why You Should Attend
gene-regulation.com provides free access to essential gene regulation data that can accelerate your research.
Understanding how genes are regulated is fundamental to advancing fields like cancer biology and developmental studies.
In this webinar, you will learn how to leverage powerful tools such as Match, P-Match, and CMA within the free TRANSFAC® platform to identify transcription factor binding sites regulating genes of interest.
And if you’re already thinking, “What’s next?” — we’ve got you covered. Get an exclusive look at how you can advance your research even further by uncovering master regulators and drug targets with the full professional power of TRANSFAC®.
Who Should Attend
Free TRANSFAC public (gene-regulation.com):
Solving Real Research Pains
Tool / Section
MATCH™
How Free TRANSFAC Helps
Predict TFBS motifs in your sequence
How Professional TRANSFAC Helps
Access to full PWM library (>10,000 matrices), covering all major TF families and conditions → higher accuracy and fewer false negatives
Tool / Section
F-MATCH™, CMA (Composite Module Analyst)
How Free TRANSFAC Helps
Analyze shared TF motifs across promoters using F-MATCH and CMA
How Professional TRANSFAC Helps
Perform true enrichment analysis with statistical scoring and promoter library customization for any organism
Tool / Section
MATCH™ + Matrix Browser
How Free TRANSFAC Helps
Simple demo of TF motif scanning
How Professional TRANSFAC Helps
Use advanced tools like Upstream Analysis, network reconstruction, and tissue-specific promoter analysis in teaching and research
Tool / Section
MATCH™
How Free TRANSFAC Helps
Manually scan sequences one by one
How Professional TRANSFAC Helps
Can perform batch analysis, cross-species promoter comparisons
Tool / Section
MATCH™
How Free TRANSFAC Helps
Find predicted motif locations
How Professional TRANSFAC Helps
Prioritize biologically relevant sites using ChIP-seq support and binding affinity scores from ML-based approach
Tool / Section
Matrix Browser
How Free TRANSFAC Helps
View matrix information and consensus sequence
How Professional TRANSFAC Helps
Access experimentally supported matrices with detailed binding context (e.g., cell type, condition, tissue)
Tool / Section
P-Match
How Free TRANSFAC Helps
Use P-Match for combined scoring
How Professional TRANSFAC Helps
Tune search with custom thresholds, apply to entire gene sets, and integrate into graphical workflows
Tool / Section
MATCH™, AliBaba2
How Free TRANSFAC Helps
AliBaba2 allows fuzzy motif matching
How Professional TRANSFAC Helps
Use modern, AI-assisted scanning with context-aware scoring, multi-matrix matching, and support for enhancers
Tool / Section
MATCH™ + manual input
How Free TRANSFAC Helps
Manual MATCH™ input one-by-one
How Professional TRANSFAC Helps
Fully integrated into graphical workflows for multiple input
How Free TRANSFAC Helps
Not supported in free version
How Professional TRANSFAC Helps
Run Upstream Analysis: connects TFBS to signaling cascades and identifies key master regulators with biological causality
What to expect – and what not to expect – from TRANSFAC Free (Public)
Compared to Pro version
|
TRANSFAC free (public) |
TRANSFAC professional (2024.2) | |
|
Data | ||
|
Factors |
6,133 |
49,372 |
|
miRNAs |
n/a |
1,772 |
|
DNA sites |
7,195 |
50,891 |
|
mRNA sites |
n/a |
67,700 |
|
Factor-DNA site links |
Yes |
68,898 |
|
miRNA-mRNA site links |
n/a |
74,550 |
|
Genes |
2,397 |
103,765 |
|
ChIP-Seq fragments |
n/a |
112,344,359 |
|
Matrices |
398 |
11,124 |
|
References |
Yes |
45,665 |
|
Promoter sequences |
n/a |
465,413 |
|
Enhancer / silencer sequences |
n/a |
231,413 |
|
Search Options | ||
|
Use of Boolean operators / advanced filtering |
No |
Yes |
|
Ontology search |
No |
Yes |
|
Customizable / exportable search results |
No |
Yes |
|
Export in FASTA and BED format |
No |
Yes |
|
Analysis Capabilities | ||
|
MATCH Suite: toolbox to analyze syntax and semantics of gene regulation |
No |
Yes |
|
Analysis workflows for ChIP-Seq and RNA-Seq data |
No |
Yes |
|
Identify shared functional attributes |
No |
Yes |
|
Data Download | ||
|
Flat file and JSON format data files |
No |
Yes |
Usage of TRANSFAC FRE (Public)
Best for:
Not ideal for: