Unlock the Benefits of TRANSFAC license
Benefits of Licensing TRANSFAC®
1. TFBS search is empowered by the biggest collection of site models known as TRANSFAC® PWM Library. In the release 2024.1 there are 10,706 matrices.
3. Find detailed information about the gene of interest including functional categorization, orthologous relationships, tissue expression profiles, transcriptional regulation of gene expression, and information on predicted enhancers and silencers.
Please note that the example report below refers to the CREB1 gene, which encodes a transcription factor. This report includes transcription factor-specific information and some other other data which may not be included for other reports.
4. Find information on 50,000 experimentally proven TFBSs with 68,900 “factor-to-site” links
5. Find information on 67,700 experimentally proven miRNA binding sites in 3’ gene regions with 74,500 “miRNA-to-mRNA” links. Identify miRNA binding sites using the integrated TargetScan database.
6. Learn about 48,900 manually curated TF interactions with other TFs, with co-activators and some other proteins
7. Launch MATCH Suite analysis and get a detailed report as a PDF file along with the primary calculated tables.
8. Identify tissue-specific regulation of your gene in focus with MATCH Suite
9. Apply inbuilt pipelines to identify TFBS combinations with combinatorial models based on sparse logistic regression (MEALR) or with CMA (Composite Module Analyst)
View details on combinatorial analysis of gene regulation
10. Run inbuilt pipelines/workflows specific for analysis of gene sets, genomic fragments, genome variations, identification of master regulatory molecules, and more.
11. Explore available TRANSFAC packages
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Select your TRANSFAC
online license
Biggest collection of transcription factors, their DNA binding models, and genes bound by them, in
a user-friendly interface
Prediction of TFBS in eukaryotic species, with a focus on human, mouse, rat, yeast, and plants,
using portal interface
Prediction of human TFBS using classic Match and MATCH Suite tools
Advanced tools for prediction of TFBS and their combinations on genomic scale using Machine Learning and AI methods
Over 200 pipelines and tools for bioinformatics analysis and modeling of NGS, RNA-seq, epigenomics, proteomics, and metabolomics data
Application Programming Interface (API) including Java-based API, R-based API, Jupiter notebook
Signal transduction and metabolic pathways, individual reactions with experimental details, protein-protein interactions (PPIs) and post-translational modifications (PTMs)
Integrated pathway visualization and modification tool
Gene-Disease-Drug-Clinical Trial assignments, disease biomarkers, drug targets, drug-disease approval status, functional classification tools
Upstream Analysis – integrated promoter and pathway analysis for identification of prospective drug targets and biomarkers
Disease molecular mechanism reconstruction and identification of prospective drug targets and treatments using a fully automatized pipeline for multi-omics data processing
TRANSFAC®
basic
TRANSFAC 2.0 including
MATCH Suite
TRANSFAC®
omics
TRANSFAC 2.0 including
MATCH Suite, and the geneXplain platform
TRANSFAC®
master-regulators
TRANSFAC 2.0 including
MATCH Suite, and HumanPSD + TRANSPATH, and the geneXplain platform
TRANSFAC®
full package
TRANSFAC 2.0 including
MATCH Suite, and HumanPSD + TRANSPATH, and the geneXplain platform, and Genome Enhancer
