Recent applications

Selection of articles reporting about TRANSFAC applications:
  • Zhou L., Yang Y., Ye Y., Qiao Q., Mi Y., Liu H., Zheng Y., Wang Y., Liu M., Zhou Y. (2024). Notch1 signaling pathway promotes growth and metastasis of gastric cancer via modulating CDH5. Aging (Albany NY). 16(16):11893–11903. Link
  • Li F., Wang J., Li M., Zhang X., Tang Y., Song X., Zhang Y., Pei L., Liu J., Zhang C., Li X., Xu Y., Zhang Y. (2024). Identifying cell type-specific transcription factor-mediated activity immune modules reveal implications for immunotherapy and molecular classification of pan-cancer. Brief Bioinform. 25(5):bbae368. Link
  • Lleshi E., Milne-Clark T., Yu H.L., Martin H.W., Hanson R., Lach R., Rossi S.H., Riediger A.L., Görtz M., Sültmann H., Flewitt A., Lynch A.G., Gnanapragasam V.J., Massie C.E., Dev H.S. (2024). Prostate cancer detection through unbiased capture of methylated cell-free DNA. iScience. 27(7):110330. Link
  • Ceroni F., Cicekdal M.B., Holt R., Sorokina E., Chassaing N., Clokie S., Naert T., Talbot L.V., Muheisen S., Bax D.A., Kesim Y., Kivuva E.C., Vincent-Delorme C., Lienkamp S.S., Plaisancié J., De Baere E., Calvas P., Vleminckx K., Semina E.V., Ragge N.K. (2024). Deletion upstream of MAB21L2 highlights the importance of evolutionarily conserved non-coding sequences for eye development. Nat Commun. 15(1):9245. Link
  • De Freitas J.T., Thakur V., LaPorte K.M., Thakur V.S., Flores B., Caicedo V., Ajaegbu C.G.E., Ingrasci G., Lipman Z.M., Zhang K., Qiu H., Malek T.R., Bedogni B. (2024). Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME. J Exp Clin Cancer Res. 43:295. Link
  • Batuhan Kisakol., Anna Matveeva., Manuela Salvucci., Alexander Kel., Elizabeth McDonough., Fiona Ginty., Daniel B Longley., Jochen H M Prehn. (2024) Identification of unique rectal cancer-specific subtypes. British J of Cancer.130,1809–1818. Link
  • Dig B. Mahat., Nathaniel D. Tippens., Jorge D. Martin-Rufino., Sean K. Waterton., Jiayu Fu., Sarah E. Blatt & Phillip A. Sharp. (2024) Single-cell nascent RNA sequencing unveils coordinated global transcription. Nature. 631, 216–223. Link
  • Sung-Joon Park., Kenta Nakai. (2024) A computational approach for deciphering the interactions between proximal and distal gene regulators in GC B-cell response. NAR Genomics & Bioiformatics. Volume 6, issue 2. Link
  • Farrim M.I., Gomes A., Milenkovic D., Menezes R. (2024) Gene expression analysis reveals diabetes-related gene signatures. Hum Genomics 18, 16. Link
  • Eni-Aganga I., Lanaghan ZM., Ismail F., Korolkova O., Goodwin JS., Balasubramaniam M., Dash C., Pandhare J. (2024). KLF6 activates Sp1-mediated prolidase transcription during TGF-β1 signaling. J Biol Chem. 2024 300(2):105605. Link
  • Hasegawa K., Tamaki M., Sakamaki Y., Wakino S. (2024) Nmnat1  Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1. Int J Mol Sci. 25(12):6384. Link
  • Abrar M., Ali S., Hussain I., Khatoon H., Batool F., Ghazanfar S., Corcoran D., Kawakami Y., Abbasi AA. (2024). Cis-regulatory control of mammalian Trps1 gene expression. J Exp Zool B Mol Dev Evol. 342(2):85-100. Link
  • Scaramuzzo RT., Crucitta S., Del Re M., Cammalleri M., Bagnoli P., Dal Monte M., Pini A., Filippi L.. (2024) β3-adREnoceptor Analysis in CORD Blood of Neonates (β3 RECORD): Study Protocol of a Pilot Clinical Investigation. Life (Basel). 14(6):776. Link
  • Cene Skubic., Hana Trček., Petra Nassib., Tinkara Kreft., Andrew Walakira., Katka Pohar., Sara Petek., zadeja Režen., Alojz Ihan., Damjana Rozman. (2024) Knockouts of CYP51A1, DHCR24, or SC5D from cholesterol synthesis reveal pathways modulated by sterol intermediates. iScience, Volume 27, Issue 9, 110651. Link
  • Jamil M.A., Al-Rifai R., Nuesgen N., Altmüller J., Oldenburg J., El-Maarri O. (2024) The role of microRNAs in defining LSECs cellular identity and in regulating F8 gene expression. Front Genet. 15: 1302685 Link
  • Coatti G.C., Vaghela N., Gillurkar P., Leir S., Harris A. (2024) A promoter-dependent upstream activator augments CFTR expression in diverse epithelial cell types. Biochim Biophys Acta Gene Regul Mech. 1867(2):195031 Link
  • Novikova S., Tolstova T., Kurbatov L., Farafonova T., Tikhonova O., Soloveva N., Rusanov A., Zgoda V. (2024) Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia. Int. J. Mol. Sci.  25(9), 4618 Link
  • Satsu H., Gondo Y., Shimanaka H., Imae M., Murakami S., Watari K., Wakabayashi S., Park S.J., Nakai K., Shimizu M. (2022) Signaling Pathway of Taurine-Induced Upregulation of TXNIP. Metabolites. 12(7),636. Link
  • Deepti P., Pasha A., Kumbhakar D.V., Doneti R., Heena S.K., Bhanoth S., Poleboyina P.K., Yadala R., Anapurna S.D., Pawar S.C. (2022) Overexpression of Secreted Phosphoprotein 1 (SPP1) predicts poor survival in HPV positive cervical cancer. Gene. 824,146381. Link
  • Song Q., Bian Q., Liang T., Zhang Y., Zhang K. (2021) Identification of immune-related genes and susceptible population of pulmonary tuberculosis by constructing TF-miRNA-mRNA regulatory network. Tuberculosis (Edinb). 131,102139. Link
  • Thompson B., Chen Y., Davidson E.A., Garcia-Milian R., Golla J.P., Apostolopoulos N., Orlicky D.J., Schey K., Thompson D.C., Vasiliou V. (2021) Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function. Ocul Surf. 22,190-203. Link
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