Synonyms:
complement receptor 3; CD11/CD18; integrin alpha-M/beta-2; MAC-1; macrophage receptor 1; Macrophage receptor complex-1; beta2-integrin:CD11B
Description:
CD11B: Integrin alpha M, a calcium ion interacting adhesion molecule that acts in cell migration, phagocytosis, and immune response, increased protein expression correlates with Alzheimer disease, leukemia, arthritis, ischemia, asthma, and multiple sclerosis
beta2-integrin: Integrin beta 2, acts in cell adhesion and immunity, upregulated in arthritis, diabetes, HIV, sclerosis, ischemic attack, Crohn disease, psoriasis, melanoma, and several cancers; gene mutation correlates with leukocyte-adhesion deficiency syndrome
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