Synonyms:
alpha IIb-integrin:beta3-integrin; GPIIb/IIIa receptor, fibrinogen receptor
Description:
beta3-integrin: Integrin beta 3, a receptor that acts in cell adhesion, angiogenesis, and platelet activation, aberrantly expressed in glioblastoma, diabetic retinopathy, female infertility, melanoma, thrombasthenia, coronary disease, and colorectal and ovarian neoplasms
alpha IIb-integrin: Integrin alpha 2b, a receptor that plays a role in cytoskeleton reorganization, calcium-dependent cell adhesion, blood coagulation, phagocytosis, and angiogenesis; gene mutations are associated with Glanzmann thrombasthenia and coronary thrombosis
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