Synonyms:
ADAM17; TACE; TNF-alpha-converting enzyme; CD156b antigen; TNF-alpha converting enzyme; TNF alpha converting enzyme; snake venom-like protease; TNF-alpha convertase; CSVP; CD156b; MGC71942; ADAM18; NISBD; NISBD1; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
Description:
ADAM metallopeptidase domain 17, involved in GPCR, EGFR, and Notch signaling, acts in TNF production, heart development, myelination, and inflammation, upregulated in arthritis, psoriasis, multiple sclerosis, and prostate and breast cancers
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