INTEGRIN ALPHA-8/BETA-1


Synonyms:

alpha8-integrin:beta1-integrin


Description:

beta1-integrin: Integrin beta 1, a laminin receptor that acts in GPCR signaling, apoptosis, cell adhesion, chemotaxis, and inflammation, aberrantly expressed in AIDS, intestinal diseases, asthma, arthritis, sclerosis, atopic dermatitis, breast and several other cancers
alpha8-integrin: Integrin alpha 8, a receptor that acts in cell adhesion, organ morphogenesis, actin filament organization, and VSMC migration and proliferation, mediates focal adhesion assembly and mesangial cell apoptosis; gene is downregulated in gastric carcinoma


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CM000003947


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