Synonyms:
alpha6-integrin:beta1-integrin
Description:
alpha6-integrin: Integrin alpha 6, a tyrosine kinase activator that acts in cell adhesion, involved in EGFR signaling, cell migration, and antiapoptosis; mRNA expression is upregulated in lung and prostate cancers, gene mutations correlate with epidermolysis bullosa
beta1-integrin: Integrin beta 1, a laminin receptor that acts in GPCR signaling, apoptosis, cell adhesion, chemotaxis, and inflammation, aberrantly expressed in AIDS, intestinal diseases, asthma, arthritis, sclerosis, atopic dermatitis, breast and several other cancers
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