Synonyms:
alpha2-integrin:beta1-integrin
Description:
alpha2-integrin: Integrin alpha 2, a laminin receptor that binds to collagen, acts in Ras signaling, cell adhesion, and blood coagulation; mRNA is upregulated in lung cancer, SNPs are associated with coronary atherosclerosis, myocardial infarction, and ischemic stroke
beta1-integrin: Integrin beta 1, a laminin receptor that acts in GPCR signaling, apoptosis, cell adhesion, chemotaxis, and inflammation, aberrantly expressed in AIDS, intestinal diseases, asthma, arthritis, sclerosis, atopic dermatitis, breast and several other cancers
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