IL-3RALPHA:IL-5RBETA


Synonyms:

IL-3R; heterodimer (alpha)&(beta=CSF2RB)


Description:

IL-5Rbeta: Colony stimulating factor 2 receptor beta low-affinity, an interleukin receptor that acts in JAK-STAT cascade, cell proliferation, and apoptosis; gene mutations are associated with pulmonary alveolar proteinosis, bipolar disorder, and schizophrenia
IL-3Ralpha: Interleukin 3 receptor alpha, plays a role in cell proliferation and regulation of cytokine secretion, may be involved in antiapoptosis and B-cell differentiation, aberrantly expressed in leukemia, HIV infection, atopic dermatitis, and skin neoplasms


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CM000051630


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