Synonyms:
IL-12R; interleukin receptor
Description:
IL-12Rbeta2: Interleukin 12 receptor beta 2, promotes IL-12 signaling, Th1 cell differentiation, NK cell activity, and IFN gamma immune responses, aberrantly expressed in type 1 diabetes, asthma, multiple sclerosis, tuberculoid leprosy, and non-small-cell lung cancer
IL-12Rbeta1: Interleukin 12 receptor beta 1, acts in cell proliferation and Th1 immune response, regulates interferon-gamma production, upregulated in common variable immunodeficiency; gene polymorphism is associated with leiomyoma, tuberculosis, and atopic dermatitis
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