Synonyms:
TSHR; thyroid stimulating hormone receptor; Hs.123078; TSHR-alpha; TSHR-beta; LGR3; hTSHR-I; MGC75129; CHNG1; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSH-R
Description:
Thyroid stimulating hormone receptor, binds to PI3K, promotes adenylyl cyclase activity and cAMP biosynthesis; increased expression of autoimmune antibodies causes Graves disease, gene mutation causes nodular goiter, hyperthyroidism, and hypothyroidism
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