Synonyms:
PDGFRbeta; PDGFR-1; PDGFR; PDGFRB; JTK12; CD140B; PDGFR1; PDGF-R-beta; IBGC4; beta platelet-derived growth factor receptor; CD140B antigen)
Description:
Platelet-derived growth factor receptor beta polypeptide, exhibits kinase activity, acts in activation of MAPK activity and chemotaxis, upregulated in breast and several other neoplasms; gene translocations are associated with myeloproliferative disorders
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