Synonyms:
SHPS1; MFR; MYD-1; Sirp-alpha-1; SIRPalpha; SIRPalpha2; PTPNS1; CD172A; Brain Ig-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; CD172a antigen; Inhibitory receptor SHPS-1; MyD-1 antigen; SHP substrate 1; Signal regulatory protein alpha-1; Tyrosine-protein phosphatase non-receptor type substrate 1 precursor; Macrophage fusion receptor; Sirp-alpha-2; Sirp-alpha-3; signal-regulatory protein alpha; BIT; P84; SIRP; SHPS-1; SIRPA
Description:
Signal-regulatory protein alpha, induces MAPK activation, IGF receptor signaling, apoptosis, and stress fiber formation, acts in T cell activation, cell adhesion, and phagocytosis, inhibits NF-kappaB cascade, cytokine secretion, and bone resorption
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