Synonyms:
IL-27A:IL-27B
Description:
IL-27A: Interleukin 27, a subunit of heterodimeric cytokine complex that stimulates T cell proliferation and regulatory T cell development, inhibits apoptosis; mRNA is upregulated in aplastic anemia and sclerosis and is downregulated in thrombocytopenia
IL-27B: Epstein-Barr virus induced gene 3, a cytokine that induces T cell proliferation and IFN-gamma biosynthesis, upregulated in lymphoproliferative disorders and Hodgkin and adult T-lymphoma; decreased mRNA expression is associated with Behcet disease
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