Synonyms:
sclerostin; VBCH; SOST; SOST1; sclerosteosis; CDD
Description:
Sclerosteosis, inhibits BMP and Wnt signaling pathways, acts in induction of apoptosis, ossification, and limb morphogenesis, downregulated in spondylitis; gene mutations correlate with Van Buchem disease, osteochondrodysplasias, and hyperostosis
Access the full report of HumanPSD™/TRANSPATH® (requires subscription):
Request a license for HumanPSD™/TRANSPATH® and other geneXplain products here.