Synonyms:
IL-12p35:IL-12p40; IL-12; IL-12p70; Il12b:Il12a; interleukin 12
Description:
IL-12p40: Interleukin 12B, acts in Th1 type immune response, leukocyte chemotaxis, and NF-kappaB cascade, upregulated in skin neoplasms, Crohn disease, psoriasis, and AIDS; gene polymorphisms are associated with cerebral malaria, leprosy, tuberculosis, and diabetes
IL-12p35: Interleukin 12A, a cytokine that regulates leukocyte chemotaxis, antimicrobial humoral response, and interferon-gamma production, aberrantly expressed in Crohn disease, Behcet and Sezary syndromes; decreased mRNA expression causes multiple sclerosis
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